Mesothelioma - What Causes Mesothelioma Other Than Asbestos? Asbestos is the sole reason for mesothelioma. It can affect the linings of the lungs, abdomen (peritoneal msothelioma) and the heart (pericardial msothelioma). Other risk factors are radiation therapy for cancer, genetics, and minerals that are similar to asbestos like silica and
